Interferon, antivirals and therapy targets

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Metz DH, Esteban M, Danielescu G.The formation of virus polyribosomes in L cells infected with vaccinia virus. J Gen Virol. 1975 May;27(2):181-95.

Metz DH, Esteban M, Danielescu G.The effect of interferon on the formation of virus polyribosomes in L cells infected with vaccinia virus. J Gen Virol. 1975 May; 27(2):197-209.

Popa LM, Repanovici R, Samuel I, Smelt D, Portocala R.Identification of Sendai virus neuraminidase and hemagglutinin subunits.FEBS Lett. 1975 Mar 1;51(1):270-3.

Popa LM, Repanovici R, Samuel I, Portocala R.Specific cleavage of Sendai virus nucleocapsid protein subunits during virus storage. Arch Virol. 1975; 48(4):289-95.

Danielescu G, Anton D, Botnariuc I, Mutiu A, Cajal N. Effect of interferon on virus-transformed and tumor cell lines. Virologie. 1983 Jul-Sep;34(3):167-75.

Repanovici R, Iliescu R, Lober G, Cajal N, Popa LM. Effect of some anthracycline antibiotics on the neuraminidase activity of Sendai virus and its isolated glycoproteins. Acta Virol. 1985 Dec;29(6):499-504.

Popa LM, Repanovici R, Iliescu R, Mihalache O, Cajal N. Some physico-chemical and biological properties of egg-Sendai virus with altered haemagglutinin-neuraminidase protein. Acta Virol. 1985 Dec;29(6):461-5.

Zuivertz A, Tomas S, Popescu A, Cristescu C, Tomas E Effects of asymmetrical triazine copper complexes on superoxide radical formation and on the Sendai virus multiplication. Virologie, 1988, Jul-Sep;39(3):217-20.

C. Cernescu, L Popescu, S Constantinescu, S Cernescu Antiviral effect of lithium chloride. Virologie. 1988 Apr-Jun;39(2):93-101.

Danielescu G, Maniu H, Georgescu T, Cajal N. Gamma interferon induced in human leukocytes by phytohemagglutinin: its production and biological characteristics Virologie. 1988 Apr-Jun;39(2):121-9.

St. N. Constantinescu, Cernescu C. Balta F., Maniu H., Popescu L.M., The priming effect of human interferon alpha is mediated by Protein kinase C. J. Interferon Res., 1990, 10, 589-598.

St. N. Constantinescu, C. Cernescu, L.M. Popescu, Effect of Protein kinase C inhibitors on viral entry and infectivity FEBS Letters, 1991, 292, 31-33.

Dumitrescu M, Jucu V, Zaharia CN, Belu O, Rojanschi D, Diaconu C, Talos D, Panaitescu M. The action of amphiphilic drugs on human fibroblasts in vitro. Their possible use in antiviral and antitumor chemotherapy. Rev Roum Virol. 1993 Jul-Dec;44(3-4):211-21.

Ruta SM, Cernescu C. Syncytium forming capacity of HIV 1 strains is inhibited by pretreatment of CD 4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon. Rev. Roum. Virol., 1994, 45, 3-4

Ruta SM. Perspective ale terapiei cu citokine in infectia HIV. Studii si cercetari de virusologie, 1995, 25(1), 9-11.

Sahini VE, Dumitrescu M, Volanschi E, Birla L, Diaconu C. Spectral and interferometrical study of the interaction of haemin with glutathione. Biophys Chem. 1996 Feb 8;58(3):245-53.

Repanovici R, Plesa A, Anton G. Transformation of Escherichia coli cells by pH 2.3 plasmid DNA treated with psoralens plus near-UV light. J Photochem Photobiol B. 1997 Jan;37(1-2):26-30.

Petrescu AL, Petica M, Barnaure F, Athanasiu P., Immunogenicity of inactivated vaccines prepared with parainfluenza viruses type 1 and type 3, administered experimentally by nasal or oral route.Rom J Virol. 1998 Jan-Dec;49(1-4):97-115.

Diaconu CC, Szathmari M, Keri G, Venetianer A. Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232. Br J Cancer. Nature Publishing Group,1999 Jun;80(8):1197-203.

Ruta SM, Loredana Manolescu, The continous reevaluation of antiretroviral therapy in HIV infection , Std. cerc. Virusologie 2000, 30 (2), 1-8.

Diaconu CC, Chitu V, Tardei G, Bleotu C, Ruta SM, Grancea C, Zaharia CN, Cernescu CE, Quantitative semiautomated fluorescence-based assays for biological evaluation of new anti-HIV agents, Cytometry, Wiley-Liss, Inc., ISSN: 0196-476342, 2000, 2, 146.

Chivu M, Alexiu I, Bleotu C, Rojanschi D, Crisan I, Pop D, Jucu V., Mutiu A., Activitatea antivirala a unor compusi de tip flavonoid de extractie naturala. Actiunea quercetinei asupra multiplicarii virusului herpes simplex in vitro, Std. cerc. Virusologie 2000, 30 (2): 41 - 47.

Diaconu CC, Volanschi E., Factori celulari implicaÅ£i în rezistenÅ£a multiplă la medicamente – stategii raÅ£ionale de evaluare ÅŸi chemoprevenÅ£ie, Std. cerc. Virusologie, 2002, 31, 2, 23-34.

Cornitescu M, Chivu M, Cernescu C, Fluorimetric data regarding the combined in vitro action of quercetin and its solvent DMSO on plasma membrane”, Std. cerc. Virusologie 2002, 32 (2): 68-73.

Cornitescu M, Chivu M, Cernescu C, Dimethyl sulfoxide prevents the location of quercetin in the cell plasma membrane, Proceedings of the Romanian Academy, 2003, Vol 5, No 1-2, 79-84

Ruta SM., Sultana C, Manolescu L, Cernescu C. Model in vitro pentru testarea efectului antiherpetic al inhibitorilor nonsteroidieni ai inflamatiei Std. cerc. Virusologie 2003,33(2), 31-37.

Diaconu CC, Szathmari M, Venetianer A., Antiproliferative and apoptosis-inducing effects of hemin in hepatoma cells. Ann N Y Acad Sci. 2003 Dec;1010:311-5.

Chivu M, “Molecule matriceale intercelulare în cancer”, cap. Osteopontin p. 44 – 56, red. Dumitru Miscalencu, Florica Mailat, Edit. Univ. Bucuresti 2003.

Van Den Bogaert A, Kaneva R, Schumacher J, De Zutter S, Schulze TG, Becker T, Richter C, Kapur L, Diaconu CC, Ohlraun S, Propping P, Rietschel M, Nöthen MM, Cichon S, Linkage disequilibrium analysis in a susceptibility region for bipolar affective disorder on 8q24, American Journal of Medical Genetics, 2003. Wiley-Liss, USA, ISSN: 0148-7299, 122B/1, 61.

Gheorghiu M, Bara C, Pasarica D, Brasoveanu L, Bleotu C, Toparceanu F, Trandafir T, Diaconu CC. Ethanol-induced dysfunction of hepatocytes and leukocytes in patients without liver failure. Roum Arch Microbiol Immunol. 2004; 63, 5-33.

Paus S, Rietschel M, Schulze TG, Ohlraun S, Diaconu CC, Van Den Bogaert A, Maier W, Propping P, Cichon S, Nothen MM. Systematic screening for mutations in the human N-methyl-D-aspartate receptor 1 gene in schizophrenic patients from the German population. Psychiatr Genet. 2004, 14, 233-234.

Giambasu M, Diaconu CC., Hillebrand M, Electronic Structure Of Some Antiviral Compounds, Internet Electronic Journal of Molecular Design, Bio Chem Press, USA, ISSN 1538-6414, 3, 73 – 82, 2004.

Puiu L., Constantin MC., Simioana MD., Hotnog D., Diaconu CC., Brasoveanu L., Modulation of drug-induced apoptosis in breast cancer cell lines, Anticancer Research ISSN: 0250-7005, 2004,, 24, 5D.

Petrusca DN, Petrescu A, Vrabie C, Niculescu L, Jinga V, Diaconu C, Brasoveanu L. Cell cycle regulatory factors in juxta-tumoral renal parenchyma. Rom J Morphol Embryol. 2005, 46, 117-22.

Diaconu CC., Tone M., Ruta SM., Bleotu C., Cernescu C., Volanschi E., Spectral study of the interaction of hemin with some HIV-1 V3 synthetic peptides. Proceedings of the Romanian Academy series B, 2005, vol. 7 (1), 15-22.

Ionescu S, Diaconu CC, Hillebrand M. Theoretical Study of Some Verapamil Derivatives. International Journal of Quantum Chemistry, 2006, JOHN WILEY & SONS INC, 106, 1457-1464