Department of Molecular Virology

Publications

Books

Adriana Pleșa, Gabriela Anton, Simona Ruță. Diagnosticul de laborator al infecției cu papilomavirusuri umane (HPV). 2018, in cartea “Leziuni precursoare ale cancerului de col uterin” Ed Univ “Carol Davila”
Adriana Pleşa, Iulia Virginia Iancu, Anca Botezatu, Irina Huica, Mihai Stoian, Gabriela Anton. The involvement of epigenetic mechanisms in HPV induced cervical cancer. Book: Human Papillomavirus. Editura InTech/Croaţia. 2016, p 191-241. ISBN 978-953-51-239-9
Anca Botezatu, Iulia V. Iancu, Oana Popa, Adriana Pleşa, Dana Manda, Irina Huica, Suzana Vladoiu, Gabriela Anton, Corin Badiu. Carcinogenesis in Human - The Multifactorial Foundation and Deciphering the Mechanisms-Mechanisms of oncogene activation, Book edited by: Dmitry Bulgin, ISBN 978-953-51-4382-6, Published: March 2, 2016 under CC BY 3.0 license.
Gabriela Anton, Adriana Pleşa, Coralia Bleotu, Anca Botezatu, Mihai Stoian, Marina Anton, Lorelei Braşoveanu. Human Papillomaviruses Oncoproteins. Oncogene and Cancer - From Bench to Clinic, Edited by Yahwardiah Siregar, 486 pages, Publisher: InTech, Chapters published 2013 under CC BY 3.0 license DOI: 10.5772/3217. ISBN 978-953-51-0858-0.
Adriana Pleşa. Vaccinuri profilactice si terapeutice impotriva papilomavirusurilor. Capitol in Infectia colului uterin cu virusul papiloma uman- ghid theoretic si practic de diagnostic si conduita terapeutica. Editura Universitară Carol Davila, 2010 ISBN 978-973-708-489-9.

Selected Medical Virology Papers

PAPILLOMA VIRUSES

Alina Fudulu, Adrian Albulescu,Gabriela Anton. Human papillomaviruses’ proteins with clinical utility. J Immunoassay Immunochem. 2019, 40(1):81-90
Iulia V Iancu, Adrian Albulescu, Alina Fudulu, Adriana Pleșa, Irina Huică, Demetra Socolov, Gabriela Anton, Anca Botezatu. HOXA11AS expression pattern in cervical cancer precursor lesions. National Congress of the Federation of Romanian Cancer Societies, 4-7 Oct 2018, Sinaia
Iulia V Iancu, Gabriela Anton, Anca Botezatu, Irina Huică, Anca Nastase, Demetra Socolov, Anca Stanescu, Olimpia Dima, Nicolae Bacalbasa, Adriana Pleşa. LINC01101 and LINC00277 expression levels as novel factors in HPV‐induced cervical neoplasia. Journal of cellular and molecular medicine. J Cell Mol Med. 2017, 21(12):3787-3794. IF- 4,302.
Iulia V. Iancu, Adriana Pleşa , Anca Botezatu, Irina Huica, Anca D. Stanescu, Demetra Socolov, Gabriela Anton. E5HPV16 mRNA expression pattern analysis in patients with cervical lesions in viral status context. Roum Arch Microbiol Immunol. 2015, 74(1-2):33-39.
Adriana Pleşa, Gabriela Anton, Iulia Iancu, Carmen C Diaconu, Irina Huica, Anca Stanescu, Demetra Socolov, Elena Nistor, Elena Popa, Mihai Stoian, Anca Botezatu. Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients. Arch Virol. 2014, 159(12): 3305-3320. IF-2.390.
Adriana Pleşa, Gabriela Anton, Iulia Iancu, Carmen C. Diaconu, Irina Huica, Anca stanescu, Demetra Socolov, Mihai Stoian, Anca Botezatu. The role of HPV16 viral variants in the progression of dysplastic lesions. “Academician Nicolae Cajal” Symposium – Virology and molecular medicine genomics, molecular and cellular biology. March 27-29, 2013, pg 10, Bucharest.
Adriana Pleşa, Irina Huica, Iulia Iancu, Elena Cernescu, Anca Botezatu. E5 HPV16 expression in cervical lesions. “Academician Nicolae Cajal” Sympozium, March 28-31 2012, pg 20, Bucharest.
Gabriela Anton, Gheorghe Peltecu, Demetra Socolov, Florin Cornitescu, Coralia Bleotu, Zorela Sgarbura, Sergiu Teleman, Dominic Iliescu, Anca Botezatu, Cristina Goia, Irina Huica, Cristina Anton. Type-specific human papillomavirus detection in cervical smears in Romania APMIS. 2011, 119(1):1-9 IF- 2.042.
Iulia Iancu, Anca Botezatu, Cristina Goia-Ruşanu, Anca Stănescu, Irina Huică, Elena Nistor, Gabriela Anton, Adriana Pleşa. TGF-beta signalling pathway factors in HPV-induced cervical lesions. Roum Arch Microbiol Immunol. 2010 69(3):113-8.
Gabriela Anton, Demetra Socolov, Anca Botezatu, Cristina Goia, Adriana Pleşa, S. Teleman, Iulia Iancu, Cristina Anton. Viral markers in LGSIL lesions, EUROGIN, february 2010 Monte Carlo, Monaco.

EPIGENETIC MECHANISMS IN ONCOGENESIS

Anca Botezatu A, Iulia V Iancu, Adriana Pleșa, Adrian Albulescu, Alina Fudulu, Marinela Bostan, Mirela Mihaila, Irina Huică, Gabriela Anton. The involvement of E6 and E7 HPV16 oncogenes in chromatin remodelling through components of NuRD complex, 11th Symposium on Pathology, 22-24 Nov 2018, București.
Iulia V Iancu, Alina Fudulu, Adrian Albulescu, Anca Botezatu, Adriana Pleșa, Gabriela Anton, Susana Vlădoiu, Dana Manda, Corin Badiu. Expression levels of ANRIL and NEAT1 long non-coding RNAs in thyroid neoplasia, 6th National Congress of Neuroendocrinology 10-13 Oct 2018, București.
Anca Botezatu, Iulia V Iancu, Irina Huică, Adriana Pleșa, Gabriela Anton. Epigenomic approaches in cancer pathology. The 10th National Pathology Symposium, 23-25 nov, 2017, Bucharest.
Adelina Rosca, Gabriela Anton, Anca Botezatu, Aura Temereanca, Luminita Ene, Cristian Achim, Simona Ruta S. miR-29a associates with viro-immunological markers of HIV infection in treatment experienced patients. J Med Virol. 2016, 88(12):2132-2137.IF- 1.998
Anca Botezatu, Iulia Virginia Iancu, Otilia Popa, Adriana Pleşa A, Dana Manda, Marinela Bostan, Suzana Vlădoiu, Irina Huică, Gabriela Anton, Corin Badiu. Epigenetic modifications in differentiated thyroid cancer. Academician Nicolae Cajal Symposium of the Academy of Medical Sciences Romanian Academy Library, March 17 – 19, 2016, Bucharest.
Anca Botezatu, Iulia Iancu, Adriana Pleşa, Carmen C Diaconu, Gabriela Anton, Raluca Florea, Veronica Ilie, Andrei Sorop, Nicolae Bacalbaşa, Valeria Tica, Simona Olimpia Dima, Irinel Popescu. Possible epigenetics biomarkers in pancreatic oncogenesis. Academician Nicolae Cajal Symposium of the Academy of Medical Sciences Romanian Academy Library, March 17 – 19, 2016, Bucharest.
Iulia Virginia Iancu, Anca Botezatu, Adriana Pleşa, Irina Huică, Demetra Socolov, Gabriela Anton. Epigenetic alterations in cervical carcinoma. Academician Nicolae Cajal Symposium of the Academy of Medical Sciences Romanian Academy Library, March 17 – 19, 2016, Bucharest.
Anca Botezatu, Iulia Virginia Iancu, Adriana Pleşa, Demetra Socolov, Gabriela Anton. The levels of DNA methyltransferases and MBD genes expression in HPV-induced cervical lesions. Epigenetics & chromatin meetings and courses, 2016, Cold Spring Harbour Laboratory, New York, USA, abstract in Epigenetics & chromatin meetings, p 35, 2016.
Iulia Virginia Iancu, Anca Botezatu, Adriana Pleşa, Demetra Socolov, Gabriela Anton. Expression levels of PRC2 members in HPV-induced cervical lesions. Epigenetics & chromatin meetings and courses, 2016, Cold Spring Harbour Laboratory, New York, USA, abstract in Epigenetics & chromatin, p 114, 2016.
Anca Botezatu, Coralia Bleotu, Anca Nastase, Gabriela Anton, Nicolae Bacalbasa, Dan Duda, Simona O Dima, Irinel Popescu. Epigenetic Silencing of GNMT Gene in Pancreatic Adenocarcinoma. Cancer Genomics Proteomics. 2015;12(1):21-30. IF-1.54
Anca Botezatu, Iulia Iancu, Dana Manda, Adriana Pleşa, Irina Huica, Suzana Vladoiu, Gabriela Anton, Corin Badiu. DNA methylation profiles of tumor suppressor genes promoters involved in papillary thyroid carcinoma. European cancer Congress, 24-29 sept 2015, P 133, Viena Austria.
Iulia Iancu, Anca Botezatu, Adriana Pleşa, Irina Huica, Suzana Vladoiu, Dana Manda, Corin Badiu. Long non-coding RNAs (MALAT 1 and MEG3) expression profiles in papillary thyroid carcinoma. EMBO/EMBL Symposium: The non-coding genome. EMBL Advanced training centre, 18-21 oct 2015, pg192. Heidelberg, Germany.
Adriana Pleşa, Iulia Iancu, Anca Botezatu, Irina Huica, Dana Manda, Suzana Vladoiu, Gabriela Anton, Corin Badiu. Expression profile of microRNA-34b, -21 and -133a in thyroid carcinoma. EACR Conference Series, - Basic epigenetic mechanisms in cancer. 8-11 nov, 2015, P30, Berlin, Germany.
Iulia Iancu, Anca Botezatu, Adriana Pleşa*, Irina Huica, Demetra Socolov, Gabriela Anton. Histone lysine demethylases as epigenetic modifiers in HPV-induced cervical neoplasia. Romanian Biotechnological Letters. 2015, 20(2):10236-10244. I F- 0.4
Anca Botezatu, Iulia Iancu, Adriana Pleşa, Carmen C. Diaconu, Gabriela Anton, Raluca Florea, Veronica Ilie, Andrei Sorop, Nicolae Bacalbasa, Valeria Tica, Simona Dima, Irinel Popescu. Β-catenin gene expression deregulation in pancreatic adenocarcinoma. EACR Conference Series, - Basic epigenetic mechanisms in cancer. 8-11 nov, 2015, P15, Berlin, Germany.
Anca Botezatu, Razvan Socolov, Demetra Socolov, Iulia-Virginia Iancu, Gabriela Anton. Methylation pattern of methylene tetrahydrofolate reductase and small nuclear ribonucleoprotein polypeptide N promoters in oligoasthenospermia: a case-control study. Reprod Biomed Online. 2014, 28(2):225-31.IF-3.015.
Iulia Iancu, Anca Botezatu, Adriana Pleşa, Irina Huica, Gabriela Anton, Suzana Vladoiu, Dana Manda. PTCSC3 and MEG3 IncRNAs expression profile in papillary thyroid carcinoma. EACR Conference Series, - Basis epigenetic mechanisms in cancer. 8-11 nov, 2015, P16, Berlin, Germany.
Anca Botezatu, Iulia Iancu, Adriana Pleşa, Gabriela Anton, Raluca Florea, Veronica Ilie, Andrei Sorop, Nicolae Bacalbasa, Valeria Tica, Simona Dima, Irinel Popescu. Factors involved in B-Catenin gene expression deregulation in pancreatic cancer. Acad Nicolae Cajal Symposium, Conferinta de medicina translationala, 1-4 aprilie 2015, pg 27, Bucharest.
Iulia V Iancu, Anca Botezatu, Adriana Pleşa Irina Huica, Demetra Socolov, Gabriela Anton. DNMTs profile in cervical HPV infections. Acad Nicolae Cajal Symposium, Virology and molecular medicine genomics, molecular and cellular biology, May 2014., Bucharest.
Iulia Iancu, Anca Botezatu, Irina Huica, Suzana Vladoiu, Dana Manda, Corin Badiu, Gabriela Anton, Adriana Pleşa. Investigation of miR-34b gene expression levels and its potential targets in patients with papillary thyroid carcinoma. Acad Nicolae Cajal Symposium, Virology and molecular medicine genomics, molecular and cellular biology, May 2014, Bucharest
Anca Botezatu, Demetra Socolov, Iulia Iancu, Irina Huica, Adriana Pleşa, Carmen Ungureanu, Gabriela Anton. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer. J Cell Mol Med. 2013, 17(4):543-9. IF- 4.014.
Iulia Iancu, Anca Botezatu, Adriana Pleşa, Irina Huica, Demetra Socolov, Gabriela Anton. Study on the expression pattern of histone demethylases in HPV-induced cervical lesions. FEBS Journal 280 (Suppl. 1) (2013) pg.382. Saint Petersburg, Russia ISSN: 1742-4658. IF=3.98.
Iulia Iancu, Adriana Pleşa, Anca Botezatu, Demetra Socolov, Irina Huica, Anca Nastase, Gabriela Anton. Histone lysine demethylases expression in HPV induced cervical lesions. “Academician Nicolae Cajal” Symposium – Virology and molecular medicine genomics, molecular and cellular biology. March 27-29, 2013, pg 10, Bucharest.
Anca Botezatu, Cristina Daniela Goia-Rusanu, Iulia Virginia Iancu, Irina Huica, Adriana Pleşa, Demetra Socolov, Carmen Ungureanu, Gabriela Anton. Quantitative analysis of the relationship between microRNA‑124a, -34b and -203 gene methylation and cervical oncogenesis Molecular Medicine Reports; 2011, 4(1):121-128. IF- 1.554.
Anca Botezatu, Iulia Iancu, Irina Huica, Adriana Pleşa, Cristina Goia-Rusanu, Demetra Socolov, Carmen Ungureanu, Gabriela Anton. Genomic instability and DNA methylation pattern in cervical oncogenesis Trends in Genetics: Genomic Instability and Pathways of Response, Yerevan, Armenia, February 20 – 26 Feb., pg 61. 2011. IF=9.918

MOLECULAR BIOLOGY AND GENETICS

Anca Botezatu, Maria Puiu, Natalia Cucu, Carmen C Diaconu, Corin Badiu, Cosmin Arsene, Iulia-Virginia Iancu, Adriana Plesa, Gabriela Anton. Comparative molecular approaches in Prader-Willi syndrome diagnosis. Gene. 2016;10;575:353-8. IF- 2.319.
Cristina Goia-Ruşanu, Iulia Iancu, Anca Botezatu, Demetra Socolov, Irina Huică, Adriana Pleşa, Gabriela Anton. Mitochondrial DNA mutations in patients with HRHPV-related cervical lesions. Roum Arch Microbiol Immunol. 2011, 70(1):5-10.