Bioinformatics and Hardware Group

Books

Publications

1. C.N. Zaharia, Constanta Antipa, Modificari la nivelul membranei celulare pentru internalizarea virusurilor (Modifications to the cellular membranes level for the viruses internalization), Al II-lea Simpozion Acad. Nicolae Cajal "Actualitati in Virusologie si Imunologie Medicala", Vol. rezumate, p. 63, Biblioteca Academiei Romane, 29-30 martie 2006, Bucuresti

2. D. Popescu, C.N. Zaharia, S. Ion, Maria Luisa Flonta, Compensation of neurotransmitters deficiency in the synaptic cleft, Rom. J. Biophys., 16 (3), 189-204, 2006

3. C.N. Zaharia, D. Popescu, I. Stelian, Studii calitative de docking si simulare moleculara la sisteme de interes in terapia antidepresiva (Simulations of the docking conditions and molecular modeling in which liposoms may contribute to the prevention of depression and anxiety), Al II-lea Simpozion Viasan “De la medicina moleculara si celulara la medicina clinica”, Vol. rezumate, pp. 40-41, ISBN 10973-708-004-1, 13-978-973-708-004-2, 27 octombrie, 2006, Bucuresti

4. C.N. Zaharia, D. Popescu, Calcule de docking molecular pentru compusi activi biologic din clasa Hypericum perforatum (Molecular docking computation on the biological active compounds from Hypericum perforatum), St. cercet. virusol., 2006, 36 (1), 45-51

5. D. Popescu, C.N. Zaharia, Ecaterina Maries, S. Ion, The role of structural symmetry of some molecules inserted in lipid bilayers, The 14th Romanian International Conference on Chemistry and Chemical Engineering, RICCCE XIV, Program p.40, September 22-24, 2005, Bucharest - Romania

6. C.N. Zaharia, D. Popescu, Beatrice Macri, Maria Luiza Flonta, Some interactions between hypericine and models of biological membranes, The 14th Romanian International Conference on Chemistry and Chemical Engineering, RICCCE XIV, Program p.40, September 22-24, 2005, Bucharest - Romania

7. Alexandrina Nuta, C.N. Zaharia, Gabriela Diaconu, Valentin Raditoiu Naphthodiantrones with biological activity (Compusi cu structura naftodiantronica cu proprietati biologic active), The 14th Romanian International Conference on Chemistry and Chemical Engineering, RICCCE XIV, September 22-24, 2005, Bucharest - Romania, Proceedings - Volume 3, pp S07/9 - S07/16, Editura Printech, Bucuresti, 2005, ISBN: 973-718-284-7, 973-718-287-1

8. Beatrice Macri, D. Popescu, Maria-Luiza Flonta, Gh. Stoian, C.N. Zaharia, Efectul hipericinei asupra membranelor lipidice (Hypericin effect on lipid membranes), St. cercet. virusol., 2005, 35 (1), 57-63

9. C.N. Zaharia and Gabriela Anton, Genomul virusului gripal ÅŸi design-ul de primeri (Influenza virus genome and primer design), St. cercet. virusol., 2005, 35 (2), 83-99

10. D. Popescu, C.N. Zaharia, Ecaterina Maries, Localizarea moleculelor cu simetrie structurală în bistraturi lipidice plane (Location of structural symemetry molecules in plane lipid bilayers), St. cercet. virusol., 2005, 35 (2), 173-178

11. C.N. Zaharia, Z. Haschi, Un nou model de automat celular cu aplicaţii în epidemiologie (A new cellular automata model with applications in epidemiology), St. cercet. virusol., 2005, 35 (2), 179-185

12. C.N. Zaharia, Z. Hascsi, Modelling biological phenomena with agent-based extension of cellular automata, Proceedings of Advances in Intelligent Systems and Technologies, ECIT 2004, Third European Conference on Intelligent Systems and Technologies, Iasi, Romania, July 21-23, 2004

13. Z. Hascsi, C.N. Zaharia, ArtVirus and ArtEco - Simulation environments for viral epidemics and simple ecosystems, Intelligent Systems in Medicine, Selected papers from ECIT2004, Sections Modeling, Horia-Nicolai Teodorescu (Ed.), Editura Performantica, Iasi, 2004, paginile 115-124

14. C.N. Zaharia, Ecaterina Maries, D. Popescu, Maria Luiza Flonta, Role of intermolecular forces in the stochastic pore formation into plane lipid bilayers, Procceedings of the Third Workshop on Mathematical modeling on Environmental and life Sciences Problems, in Series on Mathematical Modelling of Environmental and Life Science Problems (Eds. Stelian Ion, Gabriela Marinoschi, Constantin Popa), pp. 285-294, Editura Academiei Române, Bucuresti, 2004

15. C.N. Zaharia, Dumitru Popescu, Mihai Stoian, Cai alternative in explicarea patogeniei unor afectiuni neuropsihiatrice (Supplementary pathways for the explanation of neuropsychiatric desorders pathogeny), St. cercet. virusol., 34 (1), 63-69, 2004

16. C.N. Zaharia, Alexandrina Nuta, Stefan Prodescu, Ipoteze asupra activitatii antivirale si antitumorale a hypericinei si naftodiantronelor inrudite (Hypotheses on antiviral and antitumoral activity of hypericin and related naphtodianthrones), St. cercet. virusol., 34 (2), 63-69, 2004

17. C.N. Zaharia, Impactul economic la nivelul unui judet al pandemiei de gripa (Economic impact at the county level of the influenza pandemic), Sesiunea trimestriala de comunicari stiintifice, Academia de Stiinte Medicale, Sectia biomedicala, Bucuresti, 10 ianuarie 2003

18. C.N. Zaharia, St. Kovacs, Tuition system for the management of biological hazards, Craiova Medicala Journal (U.M.F.), ISSN: 1454-6876, 5, Sup. 3, 417-420, 2003

19. C.N. Zaharia, Quantitative parameters evaluation for influenza pandemic effects in o collectivity, Craiova Medicala Journal (U.M.F.), ISSN: 1454-6876, 5, Sup. 3, 390-393, 2003

20. Al. Cristea, C.N. Zaharia, A mathematical model of a viral epidemics for an heterogenous mixing of the various individual groups, Craiova Medicala Journal (U.M.F.), ISSN: 1454-6876, 5, Sup. 3, 443-446, 2003

21. Al. Cristea, C.N. Zaharia, A mathematical model of the measles epidemic evolutions, in the presence of vaccinations and birth rate variations, 25th National Medical Informatics Conference, Extended abstracts p. 40, Timisoara, June 13 - 15, 2002

22. C.N. Zaharia, Adriana Alexandru, Marilena Ienculescu, Radu Filimon, Distributed database for clincal and viral analysis, 25th National Medical Informatics Conference, Extended abstracts p. 42, Timisoara, June 13 - 15, 2002

23. C.N. Zaharia, Al. Cristea, A simple stochastic model of the influenza propagation, 25th National Medical Informatics Conference, Extended abstracts p. 52, Timisoara, June 13 - 15, 2002

24 Al. Cristea, C.N. Zaharia, The use of the Hierarchical Modular System as Models of some viral epidemics, Medical Informatics Europe Special Topic Conference, "Healthcare Telematics Support in Transition Countries, Abstracts, p. 59, Proceedings of MIE 2001 Special Topics Conference, p. 103 - 108, Bucharest, Romania, June 7-9, 2001

25. C.N. Zaharia, Al. Cristea, The use of Generalized Neural Networks of Simulating an Viral Epidemics in a Heterogene Community Medical Informatics Europe Special Topic Conference, "Healthcare Telematics Support in Transition Countries, Abstracts, p. 59, Proceedings of MIE 2001 Special Topics Conference, p. 109 - 117, Bucharest, Romania, June 7-9, 2001

26. C.N. Zaharia, Al. Cristea, Use of an cellular automaton for studying an influenza epidemic when the virus strain is changed,12th Biochemical and Biophysical Balkan Days, Proceedings, p.123, Bucharest, May 9-12, 2001

27. C.N. Zaharia, Virusologia si Internetul (Virology and Internet), St.cerc.virusol., 31 (1), 1-12, 2001

28. Adriana Alexandru, Marilena Ianculescu, Elena Jitaru, C.N. Zaharia, Utilizarea Internetului in telemedicina si farmacovigilenta (Internet utilization in telemedicine and pharmacovigilence), St. cerc.virusol., 31 (1), 13-20, 2001

29. C.N. Zaharia, St. Kovacs, Dezvoltarea unui sistem de instruire bazat pe cunostinte pentru initierea in managementul riscurilor ce actioneaza asupra factorului uman (The development of an instruction system for management risk initiation which operates on the human factors), St. cerc.virusol., 31 (2), 41-56, 2001

30. C.N. Zaharia, Al. Petrescu, Some objective criteria for the evaluation of influenza activity between 1991 and 1999, Proceedings of the Romaian Academy, Series B, 2, 2000

31. C.N. Zaharia, Al. Petrescu, Al. Cristea, Computerized modeling of a viral epidemic, 23-nd Romanian Conference on Medical Informatics, Medinf' 2000, Iasi, 14-16 oct. 2000

32. C.N. Zaharia, Al. Cristea, Z. Haschi, Simulation of a viral epidemic, by using the individual displacements and elementary processes of virosis spreading and course for some agents, on a special area, 22-nd Romanian Conference on Medical Informatics, Medinf'99, Sibiu, 14-16 oct. 1999

33. C.N. Zaharia, Al. Cristea, A micropopulational modeling of o viral epidemic by using a special neural network, Medical Informatics Europe 1999 (MIE'99) Congress, Ljubljana, Slovenia, 22-26 aug. 1999

34. V. Enatescu, Al. Cristea, C.N. Zaharia, The use of a neural network for realizing an automated diagnostic, Eleventh International Congress of Cybernetics and Systems, R. Vallee and J. Rose (Eds), Conference Proceedings p. 112, Brunel University, Uxbridge, Middlesex, U.K., 23-27 August 1999

35. C.N. Zaharia, Z. Haschi, Al. Cristea, The use of generalized cellular automata for modeling viral epidemics, Eleventh International Congress of Cybernetics and Systems, R. Vallee and J. Rose (Eds), Conference Proceedings p. 110, Brunel University, Uxbridge, Middlesex, U.K., 23-27 August 1999

36. C. Diaconu, V. Chitu, G. Târdei, C. Bleotu, S. Ruta, C. Grancea, C.N. Zaharia, C. Cernescu, Quantitative semiautomated fluorescence-based assays for biological evaluation of new anti-HIV agents, in Future trends in quantitative cytology for clinical and research applications, Hortobagy, Hungary, 13-16 mai 1999

37. D. Popescu, C.N. Zaharia, V. Gheorghe, M. Ionescu, The dynamic simulation of a phospholipid molecule in a lipid bilayer, Rom. J. Biophys., 9, 1999

38. C.N. Zaharia, Al. Cristea, I. Ciuca, Simulation of the control of a viral epidemic by an optimized anti-epidemic programme, using a neural network adapted to a micropopulational model, Congres on the theory and applications of the neural networks, Viena, Austria, august 1998

39. C.N. Zaharia, Al. Cristea, I. Ciuca, From a complex neural network with many components to an agregated simpler neural network, International Symposium of the Neural networks and Expert Systems in Medicine and Healthcare, NNESMED, Pisa, Italy, pp 314-317, 1998

40. C.N. Zaharia, Al. Cristea, I. Ciuca, On the estimation of the epidemiological couplings between the components of an heterogenous community using a simulation of the superposition of the local epidemics in an global epidemic with the aid of an agregated neural network, International symposium of the medical applications of the neural networks, Pisa, Italia, Sept. 1998

41. Al. Cristea, C.N. Zaharia, I. Ciuca, On the estimation of the intensities of the epidemiological processes using a simulation of a viral epidemic in a compact homogenous community with the aid of an adapted neural network, International symposium of the medical applications of the neural networks, Pisa, Italia, Sept. 1998

42. C.N. Zaharia, Al. Cristea, I. Ciuca, Special forward neural networks for the modular of simple viral epidemics, Advances inSystems, Signals, Control and Computers, (V. Bajic ed.), vol II, ISBN 0-620-2335-x, IAAMSAD and SA branch of the Academy of Nonlinear Sciences, Durban, South Africa, pp 252-259, 1998

43. Al. Cristea, C.N. Zaharia, I. Ciuca, Utilization of an hierarchical modular system for modelling a partially controlled viral epidemic, Advances inSystems, Signals, Control and Computers, (V. Bajic ed.), vol II, ISBN 0-620-2335-x, IAAMSAD and SA branch of the Academy of Nonlinear Sciences, Durban, South Africa, pp 263-267, 1998

44. Constanta Rucareanu, D. Popescu, C.N. Zaharia, The procaine effects on the gramicidin channel induced in black lipid bilayers, Rom. J. Biophys., 7, 279-285, 1997

45. C.N. Zaharia, S. Alexandru, Accesul si exploatarea bazelor de date pentru cercetarea biomedicala (The exploitation and access of databases for the biomedical research), St. cerc. virusol., 26, 5-16, 1996

46. C.N. Zaharia, Al. Cristea, Empirical decompositions of overall AIDS epidemics in local epidemics using neural networks, Rev. Roum. Med. Virol., 45, 57-68, 1995

47. Margareta Dumitrescu, C.N. Zaharia, Dana Baiu, Rita Barot-Ciorbaru, Flow cytometric study of the epirubicine accumulation modulation in the human erythrocytes by a Nocardia opaca fraction, Rom. Arch. Microbiol. Immunol., 54, 43-51, 1995

48. Al. Petrescu, C.N. Zaharia, Alexandra Mihail, V. Jucu, Filofteia Bârnaure, Florica Toparceanu, Studies concerning the course of some acute respiratory diseases in nine districts of South-East area of Romania between November 1994 and April 1995. Epidemiological, viral and serological data, Rom. J. Virol., 46, 33-41, 1995

49. C.N. Zaharia, Al. Cristea, Prelucrarea unor date experimentale de virusologie prin folosirea de programe de tip “spreadsheet” (The processing of some experimental data of virology using spreadsheet type programs), St. cerc. virus., 25, 79-90, 1995

50. C.N. Zaharia, Sonia Herman, Computer testing of biophysics knowledge, Romanian J. Biophys, 15-21, 1994

51. C.N. Zaharia, Malasiera Cristea, Al. Petrescu, V. Jucu, A.I. Popescu, Investigations on the influence of the experimental infection with the herpes simplex virus type 1 on the electrophoretic mobility of some cultured cells, Rev. Roum. Virol., 45, 55-67, 1994

52. Al. Petrescu, Alexandra Mihail, C.N. Zaharia, V. Jucu, Filofteia Bârnaure, The course of some viral respiratory infections in the south-east area of romania during the cold season 1993-1994. Epidemiological, serological and viral data, Rev. roum. Virol., 45, 159-169, 1994

53. C.N. Zaharia, Data proccessing on the operation and control of a medical research equipment and on the acquisition, storage and display of data supplied by it, Romanian J. Biophys., 4, 161-171, 1994

54. C.N. Zaharia, Bibliotheque de procedes en LOTUS 1-2-3 pour le traitement rapide des donnees experimentales de laboratoire, Rev. roum. Virol., 44, 113-125, 1993

55. Al. Petrescu, C.N. Zaharia, Alexandra Mihail, V. Jucu, Filofteia Bîrnaure, Florica Topârceanu, Malasiera Cristea, Cristina Marin, Epidemiological, viral and serological studies concerning the evolution of some acute respiratories diseases between november 1992 and march 1993 in nine districts of the south-east area of Romania, Rev. roum. Virol., 44, 69-77, 1993

56. C.N. Zaharia, F. Popescu, C. Ilie, Comanda motoarelor pas cu pas si conversia A/D-D/A la interfatarea cu un spectrofluorimetru manual (The step motor command and A/D-D/A conversion at the interface with a manual spectrofluorometer), Optoelectronica, 1, 53-59, 1993

57. C.N. Zaharia, C. Ilie, F. Popescu, A microcomputer-controlled spectrophotometer, Romanian Reports in Physics, 45, 581-583, 1993

58. Al. Petrescu, Yolanda Copelovici, N. Draganescu, Filofteia Bîrnaure, Elena Gârjabu, Alexandra Mihail, C.N. Zaharia, Florica Topârceanu, Maria Teleguta, Cristina Marin, Maria Tanase, Malasiera Cristea, The evidence of circulation of some viruses in a great town of Romania during the first half of 1992, Rev. roum. Virol., 44, 243-251, 1993

59. C.N. Zaharia, M. Stoian, Use of Harvard Graphics program in processing of results obtained from investigations on involvement of some viruses in malignant human diseases, Rev. roum. Virol., 44, 253-262, 1993

60. C.N. Zaharia, A laboratory computer adapted for running also as a chronometer, Rev. Roum. Virol., 44, 263-267, 1993

61. Al. Cristea, C.N. Zaharia, Mathematical stochastic models of some typical viral epidemiological evolutions, Rev. Roum. Virol., 44, 195-205, 1993

62. C.N. Zaharia, D. Ispas, R. Alexandrescu, Derivative densitometry and analogous integration used for the analysis of some electrophoretograms, Romanian J. Biphys., 2, 59-75, 1992